Full - Scenario Solutions and End - to - End Empowerment Initiate a New Chapter in Global Beauty Collaboration

The U.S. Food and Drug Administration (FDA) website published that the tetrahydropyrimidine carboxylic acid (also known as ectoin) independently developed by Freda Biotechnology has successfully passed the DMF filing of the FDA for active pharmaceutical ingredients (API) (DMF filing No.038868), becoming one of the two products of the same type in the world that have passed the FDA API filing.

In the vast field of the food industry, innovation is the inexhaustible driving force for the development of the industry. After unremitting efforts and strict reviews, Freda Biotechnology has officially obtained the food production license (for condiments), marking a solid and far-reaching step forward for Freda in the exploration of food innovation and the condiment sector.

Recently, the official website of the Center for Medical Device Evaluation (CMDE) under the National Medical Products Administration (NMPA) announced that sodium polyglutamate for medical devices, independently developed by Freda Biotechnology, has successfully completed Master File registration (Master File Registration No.M2024350-000). This marks the first Master File registration for such product in China.

Ectoin, is an cyclic amino acid derivative obtained through Freda’s specialized fermentation technology. As an important substance for microorganism to survive in extreme environments, ectoin can effectively bind the surrounding water molecules and form a protective layer on the surface of cell membrane, to fully protect intracellular substance from UV light and high temperature etc. Ectoin has remarkable moisturizing, soothing and repairing effects, and is widely used in various cosmetic formulations.

Sodium polyglutamate (PGA) is a water-soluble high molecule polymer produced by microbial fermentation. Structurally it is the glutamic acid linked by amide bonds. There are a large quantity of hydrogen bonds between and within the molecules of PGA, contributing to the excellent moisturizing capability of the material. Using PGA and sodium hyaluronate (HA) together can greatly increase the action time of HA, and bring smoother skin by decreasing the sticky feeling of HA.

Definition and Classification of Cosmetics

After May 1, 2025, all cosmetics registrants and filers must submit a complete safety assessment report that meets the requirements when applying for product registration or filing. In connection with the complete safety assessment, the China National Institute for Food and Drug Control (NIFDC) has issued multiple related announcements, and local drug administration bureaus have released several Q&A guides:

In 2025, driven by regulatory upgrades and technological iterations, China's cosmetics industry is undergoing a profound transformation from "scale expansion" to "quality leapfrogging."