Product Introduction

Utilizing synthetic biology technology, a fragment rich in highly bioactive sites from the amino acid sequence of human type III collagen was scientifically selected. Through efficient microbial expression and multi-stage extraction and purification, highly active and high-purity recombinant humanized type III collagen was obtained.

Basic Information

Appearance: White or off-white spongy solid

Molecular weight: Approximately 70 kDa

Purity: >95%

Product Description

Main Application: Cosmetic Ingredient

Usage Instructions: Commonly used in serums, creams, freeze-dried powders, etc. Add at the final stage of the formulation system at temperatures below 45°C.

Freeze-Dried Powder Dosage: Recommended 0.01–5%

Liquid Formulation Dosage at Room Temperature: Recommended 0.5–5%

Shelf Life: 24 months

Storage: Store sealed at room temperature

Compatibility: Good compatibility; stable with no color change

Product Efficacy

Anti-Wrinkle and Repair

(1) Significantly increases the expression of filaggrin (FLG), a key structural protein in keratinocytes, by 144.44%, promotes the formation of the keratinocyte cytoskeleton, maintains skin barrier integrity, and provides a repairing effect.

(2) Significantly enhances the expression of type IV collagen (Col-IV), a key structural protein of the basement membrane, by 176.67%, strengthens the basement membrane, and delivers anti-wrinkle and repairing benefits.

(3) Cell adhesion experiments show that recombinant humanized type III collagen notably improves fibroblast adhesion capacity by 121.85%, contributing to skin repair.

Company Profile

Since its establishment in 2008, Shandong Freda Biotech Co., Ltd. has been focusing on applying synthetic biology fermentation technology to the industrialization of high-end raw materials.In the field of cosmetic raw materials, the company takes key ingredients such as pro-xylane, 3-o-Ethyl Ascorbic Acid, and ectoin, combines with extract characteristic raw materials, thus promoting the innovation frontier of the industry.