What happens to orally supplemented GABA in the blood after it enters the human body? Existing pharmacokinetic studies show that oral γ-aminobutyric acid (GABA) exhibits the following characteristics in healthy humans: rapid absorption, mild metabolism, fast clearance with no significant accumulation tendency, and plasma GABA levels after oral administration are not affected by sex, diet, exercise, or circadian rhythm. This indicates that the dynamic changes of oral GABA in the body are relatively stable and minimally influenced by external factors.